What is combinatorial chemistry PPT?
Introduction: •Combinatorial chemistry is a technique by which large numbers of different but structurally similar molecules are produced rapidly and submitted for pharmacological assay. •This technique uses the same reaction conditions with the same reaction vessels to produce a large range of analogues.
What is combi chem?
Combi-chem or combinational chemistry is an innovative method of synthesizing multiple chemical compounds within a short turnaround time. Combinational chemistry has a wide scope of applications in the industries pertaining to semiconductors, superconductors, catalysts, and polymers.
What is the importance of combinatorial chemistry?
Combinatorial chemistry is one of the important new methodologies developed by researchers in the pharmaceutical industry to reduce the time and costs associated with producing effective and competitive new drugs. This branch of chemistry is very young, but in this short time it has had profound effects.
What is the value of combinatorial chemistry?
Combinatorial chemistry comprises chemical synthetic methods that make it possible to prepare a large number (tens to thousands or even millions) of compounds in a single process. These compound libraries can be made as mixtures, sets of individual compounds or chemical structures generated by computer software.
What is combinatorial chemistry describe the solid phase and solution phase synthesis?
A common combinatorial technique uses organic synthesis on solid support. Linker groups are attached to resin beads in the solid phase and the reactants are passed over in solution to make the intermediates and a final detachment-from-resin reaction is run to get the desired product out of the column.
What do you mean by mix and split method?
combinatorial compound libraries
The split and pool (split-mix) synthesis is a method in combinatorial chemistry that can be used to prepare combinatorial compound libraries. It is a stepwise, highly efficient process realized in repeated cycles.
