What does dimorphic RBC mean?

Dimorphic is a term used to describe two circulating red cell populations. One is the patient’s basic red cell population; the other is a second population with distinct morphological features.

What is dimorphic red cell picture?

In a dimorphic picture, the histogram may have 2 or more (multiple) red cell populations, whereas in dual populations the histogram has 2 distinct red cell populations (eg, hypochromic-microcytic and normochromic-normocytic red cells).

What is dimorphic blood film?

A dimorphic blood film is an important clue to a diagnosis of congenital or acquired sideroblastic anemia. However there are other more common causes, including the treatment of iron deficiency anemia, and blood transfusion in patients with a hypochromic microcytic anemia.

What is dimorphic Anaemia?

Dimorphic anaemia is an anaemia which is due to two deficiencies, iron- deficiency and that of nutritional macrocytic anaemia. It is thus iron-deficiency anaemia complicated by nutritional macrocytic anaemia or may equally well be regarded as nutritional macrocytic anaemia complicated by iron-deficiency.

What causes dimorphic anemia?

Dimorphic anemia is mainly caused due to two deficiencies, iron-deficiency, and nutritional macrocytic anemia. It is, therefore, iron-deficiency anemia complicated by nutritional macrocytic anemia or may be regarded as vice versa condition.

What is the interpretation of MCV when there is presence of dimorphic population of RBC?

MCV, as well as MCH and MCHC, reflect average values and may not adequately reflect RBC changes where mixed RBC populations are present, such as dimorphic RBC populations in sideroblastic anemia or combined iron deficiency anemia (decreased MCV and MCH) and megaloblastic anemia (increased MCV).

What does high RDW CV mean in a blood test?

High results If your RDW is too high, it could be an indication of a nutrient deficiency, such as a deficiency of iron, folate, or vitamin B-12. These results could also indicate macrocytic anemia, when your body doesn’t produce enough normal red blood cells, and the cells it does produce are larger than normal.

Is sideroblastic anemia dimorphic?

Sideroblastic anemias are often dimorphic. In other words, the mean corpuscular volume (MCV) may be normal or microcytic but a broad distribution of large and small cells is seen on the peripheral smear.

Is B12 deficiency anaemia?

Contents. Vitamin B12 or B9 (commonly called folate) deficiency anaemia occurs when a lack of vitamin B12 or folate causes the body to produce abnormally large red blood cells that cannot function properly. Red blood cells carry oxygen around the body using a substance called haemoglobin.