Can you use daptomycin in VRE?

Daptomycin is a lipopeptide antibiotic with potent in vitro activity against Gram-positive organisms including bactericidal activity against enterococci. Despite a lack of US FDA approval for VRE, daptomycin is considered a first-line agent for VRE-B.

What bacteria treats daptomycin?

Daptomycin is a cyclic lipopeptide antibiotic derived from the organism Streptomyces roseosporus. Daptomycin is used to treat various bacterial infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE).

What antibiotic resistant organism is VRE?

VRE stands for vancomycin-resistant enterococcus. It’s an infection with bacteria that are resistant to the antibiotic called vancomycin. Enterococcus is a type of bacteria that normally lives in the intestines and the female genital tract.

Is daptomycin bactericidal against Enterococcus?

In this context, daptomycin (DAP), a cyclic lipopeptide that retains in vitro bactericidal activity against MDR enterococci, has emerged as an interesting alternative for the management of deep-seated infections caused by these micro-organisms.

Does daptomycin cover Vrsa?

Daptomycin is active against S. aureus, including MSSA and MRSA. In vitro data demonstrate that daptomycin may have activity against VISA and VRSA. Coagulase-negative staphylococci, including methicillin-sensitive and methicillin-resistant strains are also sensitive to daptomycin.

Is VRE antibiotic resistant bacteria?

Vancomycin-resistant enterococci (VRE) are a type of bacteria called enterococci that have developed resistance to many antibiotics, especially vancomycin. Enterococci bacteria live in our intestines and on our skin, usually without causing problems.

What does daptomycin treat?

Daptomycin injection is used to treat complicated skin and skin structure infections (cSSSI). It is also used to treat infections in the bloodstream (bacteremia), including right-sided infective endocarditis. Daptomycin belongs to the class of medicines known as antibiotics.

What is the difference between daptomycin and vancomycin?

Conclusions: The results demonstrated that daptomycin was associated with a better outcome compared with vancomycin for the treatment of BSIs due to MRSA with higher vancomycin MICs.

Does linezolid cover VRE?

Linezolid is a new antibiotic that belongs to the class of oxazolidinones approved by the FDA for the treatment of VRE infections, including those with bacteremia.

Does daptomycin penetrate the urine?

Daptomycin is primarily renally excreted, with the majority of the drug remaining intact in the urine.

Is daptomycin a good antibiotic?

Daptomycin is a novel bactericidal antibiotic with excellent activity against gram-positive organisms.

What is the difference between MRSA and VRE?

MRSA can be spread by touching articles that have been contaminated by the skin of an infected or colonized person, such as towels, sheets, and wound dressings; VRE can be transmitted by touching articles soiled by an infected person’s feces.