What is bulge in hair follicle?
Hair follicles stem cells are reserved in niche called bulge (1). Bulge is located between the opening of sebaceous gland and the attachment site of the arrector pili muscle (4). Bulge stem cells are multipotent and have high proliferative potential (5).
What is the bulge cell?
The bulge cells are morphologically undifferentiated and slow-cycling under the normal conditions. Later, studies successively demonstrated that bulge cells possess stem cell properties such as high proliferative capacity and multipotency to regenerate not only hair follicles but also sebaceous glands and epidermis.
What is the dermal papilla?
The dermal papilla consists of mesenchymal cells in the hair follicle, which plays the main role in the regulation of hair growth. Maintaining the potential hair inductivity of the DPCs and the dermal sheath cells during cell culture is the most important factor in in vitro hair follicle morphogenesis and regeneration.
What is the function of the hair bulb?
The hair bulb forms the base of the hair follicle. In the hair bulb, living cells divide and grow to build the hair shaft. Blood vessels nourish the cells in the hair bulb, and deliver hormones that modify hair growth and structure at different times of life.
What are the stages of hair growth?
The hair growth cycle has three phases: the growing phase, anagen; the regressing phase, catagen; and the resting phase, telogen. The cells of anagen hairs have a high mitotic rate and are among the most rapidly replicating cells in humans.
What is the hair shaft?
Your hair shaft is the part of your hair that can be seen above your scalp. It is made of a protein called keratin, compacted and fused together.
What does a papilla look like?
Normal bumps on the tongue are called papillae. Filiform papillae are hair-like or thread-like projections on the front two thirds of the top of the tongue, and are usually pink or white in colour. Fungiform papillae also occur on the top of the tongue, with a higher concentration near the tip.
