What does a high CK total mean?

If you have higher than normal CK-MM enzymes, it may mean you have a muscle injury or disease, such as muscular dystrophy or rhabdomyolis. If you have higher than normal CK-MB enzymes, it may mean you have an inflammation of the heart muscle or are having or recently had a heart attack.

Is CK and CK-MB the same?

This test measures the amount of an isoenzyme of creatine kinase (CK) in your blood. It is called CK-MB. Your body makes 3 forms of CK, including CK-MB. CK is found in the heart, muscles, and other organs.

What is a normal CK-MB level?

3 to 5%
A significant concentration of CK–MB isoenzyme is found almost exclusively in the myocardium, and the appearance of elevated CK–MB levels in serum is highly specific and sensitive for myocardial cell wall injury. Normal reference values for serum CK–MB range from 3 to 5% (percentage of total CK) or 5 to 25 IU/L.

What is a CK-MB lab test?

Creatine kinase-MB (CK-MB) is a form of an enzyme found primarily in heart muscle cells. This test measures CK-MB in the blood. CK-MB is one of three forms (isoenzymes) of the enzyme creatine kinase (CK).

What are abnormal CK levels?

CK stands for creatine kinase, an enzyme that leaks out of damaged muscle. When elevated CK levels are found in a blood sample, it usually means muscle is being destroyed by some abnormal process, such as a muscular dystrophy or inflammation.

What are the symptoms of high CK levels?

High Creatine Kinase Levels

Muscle weakness.
Cramps.
Muscle pain.
Fatigue.
Inability to exercise (due to pain or weakness)
Dark urine.

What is MB fraction?

Abstract. An elevated level of the MB fraction of creatine phosphokinase (CPK) with normal serum myoglobin and normal CPK values was found in a case of acute idiopathic pericarditis. The elevated serum CPK-MB isozyme is suggested to be an indicator of myocardial involvement accompanying acute pericarditis.

What is the relative index ratio of total CK to CKMB?

This will create a ratio that is used as a diagnostic method. If the relative index ration of total CK to the CKMB test results is more than 2.5, then there is a good chance that the heart has been damaged. If there is no evidence of heart problems or skeletal muscle breakdown, then the kidneys may be the cause of the increased levels of CKMB.

What is a CK-MB test?

What does a high CK MB Level mean?

CK-MB This test measures the amount of an isoenzyme of creatine kinase (CK) in your blood. It is called CK-MB. Your body makes 3 forms of CK, including CK-MB. CK is found in the heart, muscles, and other organs. Because many tissues contain CK, high levels of CK can be a sign of a variety of problems.

Where is CK-MB found in the body?

Your body makes 3 forms of CK, including CK-MB. CK is found in the heart, muscles, and other organs. These include the small intestine, brain, and uterus. If you have a heart attack, injured heart muscle cells release CK-MB into your blood.